Genitourinary Surgical Consultants - Urologist, Denver, CO

Clinical Research

Genitourinary Surgical Consultants is owned by Dr. Jeffrey A. Snyder. Both he and Cynthia Ehret, PA-C, act as investigators for various clinical trials. The research department is conveniently located within the clinical office or Dr. Jeffrey A. Snyder.

The clinical department shares patient names with the research department and as a patient of Genitourinary Surgical Consultants you may receive periodic information from our research department about studies which may be of interest to you and/or that your physician has recommended.

Why are Clinical Studies important to Genitourinary Surgical Consultants?

Being involved in research programs helps our office meet its' mission to serve women and men who want to remain active and youthful by empowering them to regain control over their urinary, pelvic and sexual health. Through this association, we are able to offer a wide variety of treatment options and remain on the cutting edge of technology.

What is a Clinical Study?

A Clinical Study is designed to test the effects of a medication, medical treatment or device on a group of volunteers. A group of professionals called the Institutional Review Board or IBR carefully review study activities and is responsible for the safety and well-being of the study volunteers.

Who can be in a Clinical Study?

People with the condition being studied as well as healthy people can volunteer to participate in clinical studies. Each study has specific requirements for participants. The Principle Investigator conducting the study will review the volunteer's medical history and study requirements to determine eligibility. Study procedures, benefits and known risks will be explained to the volunteer prior to participating in the study. This discussion is called the Informed Consent.

What are the benefits of volunteering?

Several benefits exist for the volunteer. These include:

Increases the participants understanding of the condition and allows the participants to meet other people who have the same problem, which strengthens the participants support network.
Participants receive study related medical care such as examination, medication, laboratory work and treatment at no or little cost.
Frequently participants are compensated for the time and travel
Participants are giving back to the community by helping researchers find new treatments and/or medications as well as helping the researchers uncover new information about the condition and therapies.

At this time we are currently recruiting patients for the following studies:

Benign Prostatic Hyperplasia (BPH)
Stress Urinary Incontinence (SUI)
Nocturia
Stress Urinary Incontinence (SUI)-surgical procedure
Prostatitis

If you have any of these conditions, you may be eligible to participate in a clinical trial. If you're interested in being screened, please contact 303.320.0120.

Below are research studies we are currently recruiting for.

Study 1:
Males aged 45 years old and up with symptoms of BPH for at least 1 year. Symptoms include a diminished flow rate, frequently getting up in the night to urinate, hesitancy and straining while urinating, dribbling after urination, and feeling of incomplete bladder emptying. This study drug is a one-time injection into the prostate. Subjects cannot have had any surgical treatments for their BPH such as greenlight/PVP laser, TURP, TUMT, TUNA etc. If subjects are on medications to treat BPH, they would need to stop them prior to randomizing into the study. Patients on blood thinners/NSAIDs would have to stop them 5 days before the injection. Subjects cannot have had prostatitis in the last 6 months. Study runs for 1 year.
Study 2:
Males aged 40 years old and up with symptoms of BPH for at least 3 months. Symptoms include a diminished flow rate, frequently getting up in the night to urinate, hesitancy and straining while urinating, dribbling after urination, and feeling of incomplete bladder emptying. This study drug is a natural antioxidant taken daily. If subjects are on medications to treat BPH, they would need to stop them prior to randomizing into the study. Subjects must avoid foods containing lycopene (e.g. tomatoes) for the first 6 months of the study. Study runs for 9 months, all subjects are eligible to receive the medication with no chance of receiving placebo during the final 3 months of the study.
Study 3:
Males aged 65 years old and up with symptoms of Nocturia, waking up frequently (at least 2 times) per night to urinate. This study drug is a dissolvable tablet taken once a day before bedtime. Subjects cannot have had any surgical treatments for BPH such as greenlight/PVP laser, TURP, TUMT, TUNA etc. within 6 months of participating in the study. If subjects are on medications to treat BPH, they would need to have been on a stable dose for at least 3 months to participate. Subjects are asked to complete a voiding diary to record their urinary frequency for 3 days prior to most study visits. Study runs for approximately 4 months.
Study 4:
Males and females aged 18 years old and up with BCG recurrent or refractory non-muscle invasive bladder cancer (NMIBC). Refractory disease is defined as failure to achieve tumor-free status after 6 months of initiation of BCG therapy; recurrent disease is definied as reappearance of disease after achieving a tumor-free status by 6 months after initiation of BCG therapy. This study treatment is a weekly bladder instillation of medication for the first 6 weeks, followed by up to 10 monthly treatments. All subjects will be treated with either the study medication or mitomycin C. Subjects cannot have had metastatic bladder cancer. Study runs for 1 year.